JUVÉDERM® Ultra Plus XC

What is it?
JUVÉDERM® Ultra Plus XC injectable gel is a colorless hyaluronic acid gel that contains a small
quantity of local anesthetic (lidocaine) and is injected into facial tissue to smooth wrinkles
and folds, especially around the nose and mouth. Hyaluronic acid is a naturally occurring
sugar found in the human body. The role of hyaluronic acid in the skin is to deliver nutrients,
hydrate the skin by holding in water, and to act as a cushioning agent. The role of lidocaine
is to reduce the pain associated with injections into the skin.

What does it do?
JUVÉDERM® Ultra Plus XC temporarily adds volume to facial tissue and restores a smoother
appearance to the face. The lidocaine in the gel improves the comfort of the injection.

How is it used?
JUVÉDERM® Ultra Plus XC is injected into areas of facial tissue where moderate to severe
facial wrinkles and folds occur. It temporarily adds volume to the skin and may give the
appearance of a smoother surface.

What will it accomplish?
JUVÉDERM® Ultra Plus XC injectable gel will help to smooth moderate to severe facial wrinkles
and folds. Most patients need 1 treatment to achieve optimal wrinkle smoothing, and the
results last about 1 year.

What are possible side effects?
Most side effects are mild or moderate in nature, and their duration is short lasting (7 days or
less). The most common side effects include, but are not limited to, temporary injection site
responses such as: redness, pain/tenderness, firmness, swelling, lumps/bumps, bruising,
itching, and discoloration.

As with all skin injection procedures, there is a risk of infection.
One of the risks with using this product is unintentional injection into a blood vessel. The
chances of this happening are very small, but if it does happen, the complications can be
serious, and may be permanent. These complications, which have been reported for facial
injections, can include vision abnormalities, blindness, stroke, temporary scabs, or permanent
scarring of the skin.

Are there any reasons why I should not receive JUVÉDERM® Ultra Plus
XC (contraindications)?
Your physician will ask about your medical history to determine if you are an appropriate
candidate for treatment. The product should not be used in patients who have:
• Severe allergies marked by a history of anaphylaxis or history or presence of multiple
severe allergies
• A history of allergies to lidocaine or Gram-positive bacterial proteins